Bax protein channel formation
US6022720A · kind A · utility
4Cited by
0References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1997 |
| Grant date | Feb 8, 2000 |
| Priority date | — |
| Expiry date | Jul 17, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/829
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates, in general, to a protein that regulates programmed cell death and, in particular, to the pro-apoptotic protein, Bax, which forms channels in lipid membranes. The invention further relates to methods of identifying agonists and antagonists of Bax channel formation and/or activity and thereby agents that can be used therapeutically to promote or inhibit cell death.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.