Methods for the isolation of bacteria containing eukaryotic genes
US6022730A · kind A · utility
Inventor
Key dates
| Filing date | Sep 25, 1996 |
| Grant date | Feb 8, 2000 |
| Priority date | — |
| Expiry date | Sep 25, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/79
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Bacteria containing eukaryotic and/or viral genes, and often having highly pleiomorphic morphology, are obtained by culturing virally-infected eukaryotic cells under aseptic, low oxygen conditions. The bacteria so produced express products encoded by the eukaryotic genes. Analyses indicate that several isolates obtained from culturing retrovirally-infected human brain capillary endothelial cells express human-specific genes previously mapped to widely separated human chromosomes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.