Patent · US Expired

Methods for the isolation of bacteria containing eukaryotic genes

US6022730A · kind A · utility

1Cited by
2References
14Claims
0Family size

Inventor

Key dates

Filing dateSep 25, 1996
Grant dateFeb 8, 2000
Priority date
Expiry dateSep 25, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/79
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Bacteria containing eukaryotic and/or viral genes, and often having highly pleiomorphic morphology, are obtained by culturing virally-infected eukaryotic cells under aseptic, low oxygen conditions. The bacteria so produced express products encoded by the eukaryotic genes. Analyses indicate that several isolates obtained from culturing retrovirally-infected human brain capillary endothelial cells express human-specific genes previously mapped to widely separated human chromosomes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.