Pharmaceutical formulation of human-growth hormone pretreated with zinc salt
US6022858A · kind A · utility
7Cited by
12References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 23, 1998 |
| Grant date | Feb 8, 2000 |
| Priority date | — |
| Expiry date | Jul 23, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/27
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical formulation comprising a growth hormone pretreated with zinc and optionally lysine or calcium ions shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.