Compositions and methods for stimulating bone growth
US6022887A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Dec 12, 1997 |
| Grant date | Feb 8, 2000 |
| Priority date | — |
| Expiry date | Dec 12, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P19/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein X in each of formulas (1) and (2) represents a substituted or unsubstituted alkylene, alkenylene, or alkynylene linker of 2-6C; PA1 Y represents one or more carbocyclic or heterocyclic rings; when two or more rings are present in Y, they may optionally be fused; and PA1 R' represents a cation, H or a substituted or unsubstituted alkyl group of 1-6C; and PA1 the dotted lines represent optional .pi.-bonds, PA1 promote bone formation and are thus usefull in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgery, and post-dental implantation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.