Compositions and methods for treating mast-cell mediated conditions
US6022969A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 14, 1995 |
| Grant date | Feb 8, 2000 |
| Priority date | — |
| Expiry date | Sep 14, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel compounds, compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders are described. The compounds, compositions and methods are effective for the prevention and treatment of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis, as well as other types of immunomediated inflammatory disorders, such as rheumatoid arthritis, conjunctivitis and inflammatory bowel disease, various dermatological conditions, as well as certain viral conditions. The compounds comprise potent and selective inhibitors of the mast cell protease tryptase. The compositions for treating these conditions include oral, inhalant, topical and parenteral preparations as well as devices comprising such preparations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.