Solid microparticles for gene delivery
US6025337A · kind A · utility
32Cited by
10References
40Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1996 |
| Grant date | Feb 15, 2000 |
| Priority date | — |
| Expiry date | Jun 7, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A target-specific gene delivery system is made of enzymatically degradable gelatin and nucleic acids (DNA or RNA) microparticles with a linking moiety or a targeting ligand attached to the surface. The delivery system can be made by a simple method. Targeting ligands can be attached to the microparticle directly or via a linking moiety. The linkage design allows the attachment of any molecule onto the microparticle surface including antibodies, cell adhesion molecules, hormones and other cell-specific ligands.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.