Patent · US Expired

Mucosal administration of pneumococcal antigens

US6027734A · kind A · utility

27Cited by
2References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 30, 1994
Grant dateFeb 22, 2000
Priority date—
Expiry dateSep 30, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Mucosal administration, particularly intranasally, of killed whole pneumococci, lysate of pneumococci and isolated and purified PspA, as well as immunogenic fragments thereof, particularly when administered with cholera toxin B subunit, provides protection in animals against pneumococcal colonization and systemic infection. The ability to elicit protection against pneumococcal colonization in a host prevents carriage among immunized individuals, which can lead to elimination of disease from the population as a whole.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.