Esters of (+)-.alpha.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol
US6028083A · kind A · utility
17Cited by
36References
58Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 25, 1997 |
| Grant date | Feb 22, 2000 |
| Priority date | — |
| Expiry date | Jul 25, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to esters of (+)-.alpha.-(2,3 Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol, pharmaceutical formulations, methods of making and methods of using these esters. These compounds antagonize the effects of serotonin at the 5HT.sub.2A receptor and are useful in treating various conditions such as, for example, psychoses such as schizophrenia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.