Patent · US Expired

5,6,7-trisubstituted-4-aminopyrido[2,3-D] pyrimidine compounds

US6030969A · kind A · utility

5Cited by
4References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 9, 1998
Grant dateFeb 29, 2000
Priority date
Expiry dateApr 9, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound having the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are defined, a method for inhibiting adenosine kinase by administering a compound thereof, a pharmaceutical composition comprising a therapeutically effective amount of a compound thereof above in combination with a pharmaceutically acceptable carrier, a method of treating cerebral ischemia, epilepsy, pain, nociperception, inflammation and sepsis in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a compound thereof, and methods for preparation thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.