5,6,7-trisubstituted-4-aminopyrido[2,3-D] pyrimidine compounds
US6030969A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1998 |
| Grant date | Feb 29, 2000 |
| Priority date | — |
| Expiry date | Apr 9, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound having the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are defined, a method for inhibiting adenosine kinase by administering a compound thereof, a pharmaceutical composition comprising a therapeutically effective amount of a compound thereof above in combination with a pharmaceutically acceptable carrier, a method of treating cerebral ischemia, epilepsy, pain, nociperception, inflammation and sepsis in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a compound thereof, and methods for preparation thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.