Dipeptide amidines as thrombin inhibitors

US6030972A · kind A · utility

Assignee

• BASF SE

Inventors

• Hans-Joachim Bohm · Schifferstadt, DE
• Hans Wolfgang Höffken · Ludwigshafen, DE
• Wilfried Hornberger · Wiesbaden, DE
• Stefan Koser · Ludwigshafen, DE
• Helmut Mack · Ludwigshafen, DE
• Thomas Pfeiffer · Kumhausen, DE
• Werner Seitz · Plankstadt, DE
• Thomas Zierke · Böhl-Iggelheim, DE

Key dates

• Filing date: Jul 30, 1997
• Grant date: Feb 29, 2000
• Expiry date: Jul 30, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K5/06165
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## where A, B, D, R.sup.1 and R.sup.2 have the meanings stated in the description, are described. The compounds are suitable for controlling diseases. The novel compounds are prepared via compounds of the formula EQU H.sub.2 N--CH.sub.2 --G--M