Oxidation process using tempo
US6031101A · kind A · utility
7Cited by
0References
15Claims
0Family size
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Key dates
| Filing date | Apr 1, 1999 |
| Grant date | Feb 29, 2000 |
| Priority date | — |
| Expiry date | Apr 1, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to an oxidation using sodium chlorite in the presence of a catalytic amount of TEMPO and sodium hypochlorite which converts the penultimate intermediate bearing a primary alcohol to the target endothelin antagonist compound of Formula I having a carboxylic acid ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.