Interaction of cyclin D1 and estrogen receptor and its use in assays
US6033843A · kind A · utility
0Cited by
0References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 1999 |
| Grant date | Mar 7, 2000 |
| Priority date | — |
| Expiry date | Apr 6, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5011
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the finding that cyclin D1 interacts with estrogen receptor to provide activation of estrogen responsive genes. The present invention provides in vitro and in vivo assays to measure the interaction. The in vivo assays may be conducted in cells which grow in response to estrogen, particularly breast tumour cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.