Patent · US Expired

Monoclonal antibodies for selective immunological determination of high molecular weight, intact laminin forms in body fluids

US6033863A · kind A · utility

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0References

28Claims

0Family size

Assignee

Hoechst GmbH · DE

Inventors

Martin Gerl · Kriftel, DE
Cornelia Steinert · Wiesbaden, DE
Manfred Quint · Wiesbaden, DE
Rupert Timpl · Gauting, DE

Key dates

Filing date	Jan 29, 1998
Grant date	Mar 7, 2000
Priority date	—
Expiry date	Jan 29, 2018

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K16/18
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Monoclonal antibodies for selective immunological determination of high molecular weight, intact laminin forms in body fluids. The present invention relates to monoclonal antibodies for the selective immunological determination of high molecular weight forms of laminin in body fluids, to a process for preparing these antibodies, and to their use for diagnosing diseases. The antibodies according to the invention preferably bind to intact, native laminin, in particular to the structures of the laminin P1 domain of the laminin which are folded in a native manner.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.