Process for the preparation of substituted aryl lactic acid containing cyclodepsipeptides with 24 ring atoms

US6033879A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Peter Jeschke · Eltville am Rhein, DE
• Gerhard Bonse · Neunburg vorm Wald, DE
• Gerhard Thielking · Burscheid, DE
• Winfried Etzel · Leichlingen, DE
• Achim Harder · Leverkusen, DE
• Norbert Mencke · Leverkusen, DE
• Horst Kleinkauf · Berlin, DE
• Rainer Zocher
• Katsuharu Iinuma · Odawara, JP
• Kouichi Miyamoto · Berlin, DE

Key dates

• Filing date: Jun 4, 1998
• Grant date: Mar 7, 2000
• Expiry date: Jun 4, 2018

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/911
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to a new process for the preparation of substituted aryllactic acid-containing cyclodepsipeptides having 24 ring atoms of the formula (I): ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 have the meaning given in the description, PA1 with the aid of fungal strains of the species Agonomycetales or enzymatic preparations isolated therefrom.