Aryl thiophene derivatives as PDE IV inhibitors
US6034089A · kind A · utility
44Cited by
2References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 28, 1998 |
| Grant date | Mar 7, 2000 |
| Priority date | — |
| Expiry date | Sep 28, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention encompasses the novel compound of Formula I useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). ##STR1## The invention also encompasses certain pharmaceutical compositions and methods for treatment of diseases by inhibition of PDE IV, resulting in an elevation of cAMP, comprising the use of compounds of Formula I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.