Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy

US6034267A · kind A · utility

Assignee

• PHOTOCURE ASA · NO

Inventors

• Karl E. Gierskcky · Sandefjord, NO
• Johan Moan · Oslo, NO
• Qian Peng · Oslo, NO
• Harald Steen · Oslo, NO
• Trond Warloe · Oslo, NO
• Alf Bjorseth · Oslo, NO

Key dates

• Filing date: Dec 5, 1997
• Grant date: Mar 7, 2000
• Expiry date: Dec 5, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/145555
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides a pharmaceutical compositions comprising a compound of formula I: EQU R.sub.2.sup.2 N--CH.sub.2 COCH.sub.2 --CH.sub.2 CO--OR.sup.1(I) wherein, R.sup.1 and R.sup.2 have any of the values defined in the specification; or a salt thereof; and a pharmaceutically acceptable carrier or excipient. The invention also provides a method for the diagnosis or photochemotherapeutic treatment of disorders or abnormalities of external or internal surfaces of the body using such compounds or salts.