Diagnostic test carrier with multilayer field

US6036919A · kind A · utility

Assignee

• Roche Diagnostics GMBH · DE

Inventors

• Detlef Thym · Mannheim, DE
• Wofgang-Reinhold Knappe · Ludwigshafen, DE
• Rudolf Pachl · Ellerstadt, DE
• Hartmut Merdes · Heidelberg, DE
• Robert D. Lorenz · Madison, US

Key dates

• Filing date: Jul 21, 1997
• Grant date: Mar 14, 2000
• Expiry date: Jul 21, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/25125
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention concerns a diagnostic test carrier for the determination of an analyte from whole blood with the aid of a reagent system contained in the carrier which includes a colour forming reagent with a test field which has a sample application side onto which the blood sample is applied and a detection side on which an optically detectable change takes place as a result of the reaction of analyte with the reagent system and which is constructed in such a way that erythrocytes present in the sample do not reach the detection side, which is characterized in that the test field comprises a transparent foil onto which a first and a second film layer are applied on top of one another and wherein the first layer located on the transparent foil scatters light considerably less in a wet state than the overlying second layer and wherein the side of the foil on which the first layer is applied which is opposite to the foil side is the detection side and the side of the second layer which is opposite to the side with which the second layer rests on the first is the sample application side. In addition the invention concerns a method for the determination of an analyte from whole …