Fluorogenic substrates for diagnosis and photodynamic treatment of tumors
US6036941A · kind A · utility
41Cited by
5References
5Claims
0Family size
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Key dates
| Filing date | May 11, 1998 |
| Grant date | Mar 14, 2000 |
| Priority date | — |
| Expiry date | May 11, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Fluorogenic substrates susceptible of fluorescence emission and photosensitization by enzyme transformation suitable for diagnosis and photodynamic treatment of tumors, consisting of fluorescent substances with photosensitization activity, chemically modified with a group quenching the fluorescence and photosensitization properties, the said quencher group being removable by the cell enzyme activity with restoration of the properties of fluorescence and photosensitization activity of the original substance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.