Processes for the remineralization and mineralization of teeth
US6036944A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 29, 1999 |
| Grant date | Mar 14, 2000 |
| Priority date | — |
| Expiry date | Apr 29, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/88
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for remineralizing one or more subsurface lesions in a tooth and/or mineralizing one or more exposed dentinal tubules in the tooth involves dispensing effective amounts of at least one water-soluble calcium salt, at least one water-soluble non-toxic divalent metal compound wherein the divalent metal is other than calcium, at least one water-soluble phosphate salt and, optionally, a water-soluble fluoride salt; mixing the salts and compound to form a non-carbonated mixture having a pH in water such that a non-carbonated aqueous solution containing the mixture has a pH of from 4.5 to about 7.0; and then applying the non-carbonated mixture as the non-carbonated aqueous solution to a surface of the tooth for a sufficient period of time to allow sufficient amounts of calcium, phosphate and, if present, fluoride, ions in the solution to diffuse into the subsurface of the tooth where the diffused ions then react to form an insoluble precipitate onto the lesions and/or exposed tubules, thereby remineralizing the lesions and/or mineralizing the tubules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.