Tsetse thrombin inhibitor
US6036958A · kind A · utility
1Cited by
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14Claims
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Key dates
| Filing date | Jul 15, 1999 |
| Grant date | Mar 14, 2000 |
| Priority date | — |
| Expiry date | Jul 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A potent and specific inhibitor of thrombin is purified from salivary gland extracts of the tsetse fly, Glossina morsitans morsitans. The inhibitor has a molecular weight of 3530 Daltons as determined by laser desorption mass spectroscopy. The inhibitor is useful as an anticoagulant and an inhibitor of platelet aggregation and in pharmaceutical and immunogenic compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.