Patent · US Expired

Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materials and methods

US6037119A · kind A · utility

2Cited by
1References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 5, 1995
Grant dateMar 14, 2000
Priority date
Expiry dateJun 5, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N9/16
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides novel purified and isolated nucleotide sequences encoding the cGMP-binding, cGMP-specific phosphodiesterase designated cGB-PDE. Also provided by the invention are methods and materials for the recombinant production of cGB-PDE polypeptide products and methods for identifying compounds which modulate the enzymatic activity of cGB-PDE polypeptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.