Method of producing L-serine by fermentation
US6037154A · kind A · utility
9Cited by
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22Claims
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Key dates
| Filing date | Dec 30, 1998 |
| Grant date | Mar 14, 2000 |
| Priority date | — |
| Expiry date | Dec 30, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/19
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
L-serine is produced by cultivating in a medium a coryneform bacterium having L-serine productivity in which an activity of at least one of phosphoserine phosphatase and phosphoserine transaminase is enhanced, preferably, further having introduced therein a gene coding for D-3-phosophoglycerate dehydrogenase in which feedback inhibition by L-serine is desensitized, allowing L-serine to accumulate in the medium, and collecting the L-serine from the medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.