Method of providing an antihistaminic effect in a hepatically impaired patient
US6037353A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 2, 1995 |
| Grant date | Mar 14, 2000 |
| Priority date | — |
| Expiry date | Mar 2, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method of providing an antihistaminic effect in a hepatically impaired patient in need thereof comprising administering to said patient an effective antihistaminic amount of a compound of the formula ##STR1## wherein R.sub.1 is hydrogen or hydroxy; PA1 R.sub.2 is hydrogen; PA1 or R.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ; PA1 n is an integer of from 1 to 5; PA1 R.sub.3 is --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; PA1 each of A and B is hydrogen or hydroxy with the proviso that at least one of A or B is hydrogen; or a pharmaceutically acceptable salt and individual isomers thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.