Transgenic mouse expressing an .beta.-Amyloid transgene
US6037521A · kind A · utility
39Cited by
2References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 1994 |
| Grant date | Mar 14, 2000 |
| Priority date | — |
| Expiry date | Nov 14, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0312
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to an animal model of human Alzheimer's disease that is useful for determining the mechanism of the disease and for developing and testing potential therapeutic drugs. More particularly, the present invention relates to the creation of transgenic non-human mammalian animals having integrated into their genome an exogenous DNA construct that encodes a portion of a .beta.-amyloid precursor protein ("APP") and that is designed to overexpress in various types of animal tissues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.