Modified Factor VII
US6039944A · kind A · utility
5Cited by
7References
19Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jun 5, 1995 |
| Grant date | Mar 21, 2000 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/4846
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The catalytic active site of Factor VII is modified to produce a compound which effectively interrupts the blood coagulation cascade. The modifications render Factor VIIa substantially unable to activate plasma Factors X or IX. Pharmaceutical compositions of the modified Factor VII are used to treat a variety of coagulation-related disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.