Process for synthesizing COX-2 inhibitors

US6040319A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Edward G. Corley · Old Bridge, US
• Ian Davies · Princeton, US
• Robert D. Larsen · Bound Brook, US
• Philip Pye · Guttenberg, US
• Kai Rossen · Hanau, DE

Key dates

• Filing date: Apr 23, 1999
• Grant date: Mar 21, 2000
• Expiry date: Apr 23, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C251/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention encompasses a process for making compounds of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1##