Process for making diaryl pyridines useful as cox-2-inhibitors

US6040450A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Ian Davies · Princeton, US
• Michel Journet · Somerville, US
• Linda Gerena · New York, US
• Robert D. Larsen · Bound Brook, US
• Philip Pye · Guttenberg, US
• Kai Rossen · Hanau, DE

Key dates

• Filing date: Sep 15, 1998
• Grant date: Mar 21, 2000
• Expiry date: Sep 15, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/61
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention encompasses a process for making compounds of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1##