Process for producing optically active .beta.-lactones
US6040465A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 10, 1999 |
| Grant date | Mar 21, 2000 |
| Priority date | — |
| Expiry date | Mar 10, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D305/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed is a process for producing an optically active .beta.-lactone represented by the general formula (I): ##STR1## wherein R.sup.1 represents an alkyl group having 1-9 carbon atoms which can be branched or a cycloalkyl group having 5-7 carbon atoms. The process comprises reacting an aldehyde represented by the general formula (II): EQU R.sup.1 CHO (II) PA1 wherein R.sup.1 is the same as defined above, with a ketene represented by the general formula (III): EQU CH.sub.2 .dbd.C.dbd.O (III) in the presence of a bissulfonamide/aluminum complex represented by the general formula (IV): ##STR2## wherein Ar represents 2,4,6-(R.sup.2).sub.3 C.sub.6 H.sub.2 (wherein R.sup.2 represents an alkyl group having 2-4 carbon atoms), Et represents an ethyl group and Ph represents a phenyl group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.