Rapid inducible beta-lactamase screen test
US6043048A · kind A · utility
30Cited by
5References
7Claims
0Family size
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Key dates
| Filing date | Jul 26, 1996 |
| Grant date | Mar 28, 2000 |
| Priority date | — |
| Expiry date | Jul 26, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/975
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In an assay for determination of beta-lactam antibiotic resistance in a target bacterial strain, the strain is grown in the presence of both a beta-lactamese inducing antibiotic and a beta-lactam indicator antibiotic [which kills or inhibits the growth of bacteria] unable to hydrolyze beta-lactam antibiotics. Growth, indicative of drug resistance in the target strain, is monitored by detecting a fluorophor released by the enzymatic cleavage of a metabolizable fluorogenic compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.