Patent · US Expired

Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof

US6043064A · kind A · utility

6Cited by

7References

18Claims

0Family size

Assignee

Bristol-Myers Squibb Company · US

Inventors

Brian L. Davis · Ripon, US
Paul M. Cino · Bound Brook, US
Laszlo J. Szarka · East Brunswick Township, US

Key dates

Filing date	Oct 22, 1993
Grant date	Mar 28, 2000
Priority date	—
Expiry date	Oct 22, 2013

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S435/886
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

An enzymatic hydroxylation process for the preparation of compounds useful as HMG-CoA reductase inhibitors and/or as intermediates in the preparation of HMG-CoA reductase inhibitors uses a microorganism or an enzyme derived from, or having the structure of an enzyme derived from, said microorganism, which is capable of catalyzing the hydroxylation process.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.