Patent · US Expired

Indolinones having kinase-inhibiting activity

US6043254A · kind A · utility

12Cited by

1References

7Claims

0Family size

Assignee

BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

Wolfgang Grell · Biberach, DE
Helmut Wittneben · Maselheim, DE
Jacobus C. A. van Meel · Mittelbiberach, DE
Norbert Redemann · Biberach, DE
Rainer Walter · Biberach, DE
Armin Heckel · Biberach an der Riß, DE
Frank Himmelsbach · Mittelbiberach, DE
Robert Haigh · Ormskirk, GB

Key dates

Filing date	Mar 26, 1999
Grant date	Mar 28, 2000
Priority date	—
Expiry date	Mar 26, 2019

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to indolinones of general formula ##STR1## wherein R.sub.1 to R.sub.3 are defined in claim 1, the isomers and the salts thereof, particularly the physiologically acceptable salts thereof which have valuable pharmacological properties, particularly an inhibiting effect on various kinases and cycline/CDK complexes and on the proliferation of various tumour cells, pharmaceutical compositions containing these compounds, their use and processes for preparing them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.