Percutaneous myocardial revascularization growth factor mediums and method
US6045565A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 2, 1998 |
| Grant date | Apr 4, 2000 |
| Priority date | — |
| Expiry date | Nov 2, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2025/0089
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Devices and methods for increasing blood perfusion within the myocardium of the heart by wounding the myocardium and applying growth factors to promote vascularization. One method includes driving spikes into the myocardium from within the heart, with the spikes being formed of biodegradable material, containing releasable growth factors, and having lumens and side holes. An alternative method utilizes non-biodegradable spikes with lumens and side holes. Another method promotes vascularization by injecting angiogenic material into holes bored into the myocardium, leaving a patent hole. Another method includes injecting angiogenic material into the myocardium without boring, leaving no patent hole. The angiogenic material can be carried in a biodegradable adhesive. Revascularization of the myocardium is promoted in one method by externally wounding the heart and applying a patch including growth factors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.