Vaccines for equine influenza
US6045790A · kind A · utility
Inventor
Key dates
| Filing date | Sep 1, 1992 |
| Grant date | Apr 4, 2000 |
| Priority date | — |
| Expiry date | Sep 1, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16151
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It is known that the human influenza virus strain A/Puerto Rico/8/34 grows particularly well in eggs and that reasserted viruses having it as a parent may also grow well in eggs. It has now been found that certain reassortants of A/PR/8/34 and equine influenza viruses, namely those which comprise the RNA7 segment from A/PR/8/34, will grow in cell culture, even though the parent equine influenza virus will not. Thus the specification describes and claims: reassorted viruses comprising genes for surface antigens of equine influenza viruses and the RNA7 segment from A/PR/8/34; methods of obtaining such viruses by reassortment; methods of propagating such reasserted viruses in cell culture, especially Vero cells; vaccines against equine influenza comprising such reassorted viruses; and methods of vaccinating equines against influenza.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.