Highly parallel and sensitive method for identifying drugs and drug targets
US6046002A · kind A · utility
29Cited by
1References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 5, 1998 |
| Grant date | Apr 4, 2000 |
| Priority date | — |
| Expiry date | Jan 5, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/68
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention features methods for identifying gene products that mediate a phenotype, such as drug resistance or sensitivity, as well as methods for identifying new bioactive compounds, by detecting differences in sensitivity of growth rate between host cells that differ in target gene product dosage (e.g., two copies of a target gene product-encoding sequence compared to one copy).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.