Patent · US Expired

Method and composition for regulating apoptosis

US6046007A · kind A · utility

4Cited by
7References
11Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMar 17, 1999
Grant dateApr 4, 2000
Priority date
Expiry dateMar 17, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K48/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Methods and compositions for preventing or inhibiting apoptosis are provided by this invention. The methods require introducing into a cell which may undergo apoptosis a nucleic acid molecule coding for a gene product having crmA biological activity or a crmA polypeptide. This invention also provides compositions and methods for maintaining T cell viability in a subject infected with the human immunodeficiency virus (HIV), by administering to the subject an effective amount of a nucleic acid molecule coding for a gene product having crmA biological activity or the gene product itself.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.