Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders

US6046166A · kind A · utility

Assignees

• Jean-Louis Dasseux · US
• Renate Sekul · DE
• Klaus Buttner · DE
• Isabelle Cornut · CH
• Gunther Metz · DE
• Jean Dufourcq · FR

Inventors

• Jean-Louis Dasseux · Mannheim, DE
• Renate Sekul · Ladenburg, DE
• Klaus Büttner · Epfenbach, DE
• Isabelle Cornut · Edingen-Neckarhausen, DE
• Günther Metz · Edingen-Neckarhausen, DE

Key dates

• Filing date: Sep 29, 1997
• Grant date: Apr 4, 2000
• Expiry date: Sep 29, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K48/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.