Process for making morphine-6-glucuronide or substituted morphine-6-glucuronide
US6046313A · kind A · utility
6Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 31, 1996 |
| Grant date | Apr 4, 2000 |
| Priority date | — |
| Expiry date | Jul 31, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
##STR1## Morphine-6-glucuronide or substituted morphine-6-glucuronide of formulae (I) is made by conjugation of a glucuronate ester and/or substituted glucuronate ester with morphine or substituted morphine in the presence of a Lewis acid catalyst and in the absence of silver catalysts and barium hydroxide and other heavy metal derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.