Iron-containing nanoparticles with double coating and their use in diagnosis and therapy

US6048515A · kind A · utility

Assignees

• Institut fur Diagnosikforschung GmbH · DE
• Der Freien Universitat Berline · DE

Inventors

• Mayk Kresse · Berlin, DE
• Detlev Pfefferer · Berlin, DE
• Rüdiger Lawaczek · Berlin, DE
• Susanne Wagner · Mittenwalde, DE
• Wolfgang Ebert · Krefeld, DE
• Volker Elste · Berlin, DE
• Wolfhard Semmler · Glienicke, DE
• Matthias Taupitz · Teltow, DE
• Josef Gaida · Berlin, DE
• Anja Herrmann · Berlin, DE
• Monika Jukl · Berlin, DE
• Udo Swiderski · Berlin, DE

Key dates

• Filing date: Jun 25, 1997
• Grant date: Apr 11, 2000
• Expiry date: Jun 25, 2017

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2446/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Modular iron-containing nanoparticles are disclosed, as well as their production and use in diagnosis and therapy. The nanoparticles are characterised in that they have an iron-containing core, a primary coat (synthetic polymer) and a secondary coat (target polymer), and optional auxiliary pharmaceutical substances, pharmaceuticals and/or adsorption mediators.