Method for preparing an influenza virus, antigens obtained and applications thereof
US6048537A · kind A · utility
15Cited by
5References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 27, 1997 |
| Grant date | Apr 11, 2000 |
| Priority date | — |
| Expiry date | May 27, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16163
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Method for preparing purified influenza antigens from a fluid containing influenza virus, comprising the steps of concentration, purification, fragmentation and, where appropriate, inactivation, characterized in that: PA0 A. either the purification step entails several ultracentrifugation steps separated by a filtration step, PA0 B. or the fragmentation step is performed on the live virus in the presence of an amphiphilic nonionic detergent, followed by a removal of undesirable substances by filtration, retaining all of the viral constituents, PA1 or these two steps are carried out in any order.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.