Hydrophilic microparticles and methods to prepare same
US6048550A · kind A · utility
62Cited by
4References
16Claims
0Family size
Inventors
Key dates
| Filing date | Oct 2, 1997 |
| Grant date | Apr 11, 2000 |
| Priority date | — |
| Expiry date | Oct 2, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/19
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention comprises a material and a method of its preparation. The material may be described as hydrophilic microparticles, comprising a cluster of organic substance with a layer of polyelectrolyte on its surface. The present invention establishes an improved method for preparing aqueous colloidal dispersions of water-insoluble organic substances using polyionic hydrophilic polymers by which the stability of the suspension is maintained after removal of the stabilizing and/or solubilizing medium of the drug. This improved method can be utilized to formulate a variety of water-insoluble organic substances.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.