Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
US6048695A · kind A · utility
117Cited by
20References
51Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 4, 1998 |
| Grant date | Apr 11, 2000 |
| Priority date | — |
| Expiry date | May 4, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel chemically modified nucleic acids with enhanced lability towards solid supports, such as glass. These modified nucleic acids can be readily affixed to solid supports, for instance, a glass surface, without first derivatizing the glass surface. High-density microarrays based on these modified nucleic acids as well as methods for preparing these microarrays are also useful.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.