Patent · US Expired

Methods for detecting cell apoptosis

US6048703A · kind A · utility

29Cited by
2References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 12, 1997
Grant dateApr 11, 2000
Priority date
Expiry dateNov 12, 2017

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/6893
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Methods for the biochemical and immunohistochemical detection of cell apoptosis are described. The methods utilize the detection and measurement of polypeptide fragments generated during apoptosis. Conditions associated with apoptosis may be detected by the methods of this invention. Methods are also presented for the screening of potential therapeutic compounds which inhibit or stimulate apoptosis. Kits for detection of apoptosis and diagnosis of diseases are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.