Patent · US Expired

Benzothiophene, benzofuran and indole compounds

US6048875A · kind A · utility

38Cited by
2References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 26, 1999
Grant dateApr 11, 2000
Priority date
Expiry dateApr 26, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound of formula (I): ##STR1## wherein: X represents oxygen, sulphur, or NR.sub.3 wherein R.sub.3 is as defined in the description, PA1 Y represents oxygen, sulphur, NR.sub.3, or may a single bond when X represents NR.sub.3, PA1 Z represents nitrogen, carbon, or CH, PA1 A represents a single bond, alkylene (optionally substituted), arylene, cycloalkylene, heterocycle, or --SO.sub.2 --R.sub.4 -- wherein R.sub.4 is as defined in the description, PA1 W represents hydroxy, alkoxy, aryloxy, arylalkoxy, cycloalkyloxy, heterocycle bonded to oxygen, amino, or hydroxyamino, PA1 Ra, Rb, Rc, Rd, which may be the same or different, each independently of the others are as defined in the description, PA1 R.sub.1 represents aryl substituted by one to five identical or different substituents, each independently of the others, PA1 R.sub.2 represents hydrogen, alkyl, aryl, arylalkyl, cycloalkyl, heterocycle, heterocycloalkyl, or another group as defined in the description, isomers and addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same which are useful in the treatment of thrombosis, pathologies for which the origin is thrombosis, o…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.