Patent · US Expired

Amide derivatives and medicinal compositions thereof

US6048884A · kind A · utility

4Cited by
2References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 7, 1999
Grant dateApr 11, 2000
Priority date
Expiry dateMay 7, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

An amide derivative represented by the following general formula (I) or a salt thereof and a pharmaceutical composition containing the amide derivative and a pharmaceutically acceptable vehicle. ##STR1## (The symbols in the formula have the following meanings. (wherein PA1 A: heteroarylene; PA1 X: bond, O, S, --NR.sup.5 --, --NR.sup.5 CO--, --NR.sup.5 CONH--, --NR.sup.5 SO.sub.2 -- or --NR.sup.5 C(.dbd.NH)NH--; PA1 R.sup.1 : --H, -optionally substituted lower alkyl, -optionally substituted aryl, -optionally substituted heteroaryl or -optionally substituted cycloalkyl; PA1 R.sup.2a, R.sup.2b : --H or -lower alkyl, which may be the same or different; PA1 R.sup.3 : --H or -lower alkyl; PA1 R.sup.4a, R.sup.4b : --H or --OH, which may be the same different, or R.sup.4a and R.sup.4b are taken together to form .dbd.O or .dbd.N.about.O-lower alkyl; and PA1 R.sup.5 : --H or -lower alkyl.)

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.