Use of .gamma.-tocopherol and its oxidative metabolite LLU-.alpha. in the treatment of natriuretic disease
US6048891A · kind A · utility
34Cited by
4References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 17, 1998 |
| Grant date | Apr 11, 2000 |
| Priority date | — |
| Expiry date | Dec 17, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is generally related to the discovery of the therapeutic benefit of administering .gamma.-tocopherol and .gamma.-tocopherol derivatives. More specifically, the use of .gamma.-tocopherol and racemic LLU-.alpha., (S)-LLU-.alpha., or .gamma.-tocopherol derivatives as antioxidants and nitrogen oxide scavengers which treat and prevent high blood pressure, thromboembolic disease, cardiovascular disease, cancer, natriuretic disease, the formation of neuropathological lesions, and a reduced immune system response are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.