Tumor radiosensitization using gene therapy
US6051218A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Feb 2, 1996 |
| Grant date | Apr 18, 2000 |
| Priority date | — |
| Expiry date | Feb 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method of radiosensitizing a tumor in a subject by contacting the tumor with a cytokine or a nucleic acid molecule encoding a cytokine. The invention also provides a method of radiosensitizing a tumor in a subject by administering, at a site other than the tumor, a cell genetically modified to express a cytokine. The invention further provides a method of reducing the severity of a cancer in a subject by administering a cytokine at the site of the tumor or by immunizing the subject at a site other than the tumor with tumor cells genetically modified to express a cytokine, and treating the tumor with radiotherapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.