Template induced patterning of surfaces and their reversible stabilization using phase transitions of the patterned material

US6051372A · kind A · utility

Assignee

• NIMBUS Biotechnologie GmbH · DE

Inventors

• Thomas Bayerl · London, GB
• Gero Decher · Eltville am Rhein, DE
• Thomas Braunschweig · Leipzig, DE

Key dates

• Filing date: Sep 9, 1997
• Grant date: Apr 18, 2000
• Expiry date: Sep 9, 2017

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2600/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A two-dimensional patterning of a three-dimensional surface by a template molecule (or object) involving non-covalent interactions between the template and the surface and the reversible fixation of the pattern by undergoing a phase transition in the patterned material. In this invention the surface provides a multitude of mobile functional groups (matrix) which are spatially arranged by the interaction with the template, the template selects and arranges only those groups out of a multitude of functional groups which allow for a maximum of interaction between the template and the surface. The resulting pattern is then stabilized by reducing the mobility of all functional groups present on the surface by undergoing a phase transition to a state of high surface viscosity. After separation of the template and the patterned surface, the pattern on the surface is used for recognition, separation or catalytic purposes.