Methods of screening nucleic acids using mass spectrometry

US6051378A · kind A · utility

Assignee

• Genetrace Systems, Inc. · US

Inventors

• Joseph Monforte · Berkeley, US
• Thomas Shaler · Fremont, US
• Yuping Tan · Fremont, US
• Christopher Becker · Palo Alto, US

Key dates

• Filing date: Mar 4, 1997
• Grant date: Apr 18, 2000
• Expiry date: Mar 4, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/683
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

This invention relates to methods for screening nucleic acids for mutations by analyzing nonrandomly fragmented nucleic acids using mass spectrometric techniques and to procedures for improving mass resolution and mass accuracy of these methods of detecting