Vectors and methods for providing cells with additional nucleic acid material integrated in the genome of said cells
US6051430A · kind A · utility
9Cited by
4References
19Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | May 7, 1999 |
| Grant date | Apr 18, 2000 |
| Priority date | — |
| Expiry date | May 7, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel elements for improving genetic engineering techniques for producing recombinant nucleic acid molecules and/or recombinant cells. The novel elements are capable of integrating desired nucleic acid material into other nucleic acid materials, specifically into the genome of a host cell. The novel elements are derived from or based on transposons, in particular from the Tc/Mariner superfamily. In particular, the essential elements of Tc1 enabling excision and pasting of the desired nucleic acid material are provided, together with the relevant transposase activity in cis or in trans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.