Cloning and expression of host-protective immunogens of IBDV
US6054126A · kind A · utility
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2References
14Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 23, 1992 |
| Grant date | Apr 25, 2000 |
| Priority date | — |
| Expiry date | Jun 23, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2720/10022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the cloning and characterization of the infectious bursal disease virus (IBDV) genome, to the identification of cloned genes for host-protective antigens of IBDV, to the expression of cDNA inserts encoding the whole or part of host-protective antigens of IBDV in E.coli or other host cells, and to the use of the expressed antigens in the production of virus neutralizing antibodies in chickens. The invention also relates to the production of an effective sub-unit vaccine against IBDV utilizing the expressed antigens, as well as to the use of the expressed antigens in diagnostic tests, assays and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.